Volume 25 , Issue 2 , December 2023 , Pages 6-24
Shakhawan Beebany 1 ; Saad Salem Jasim 1 ; Sevgi Samih Hidayet Arslan 2
1 Department of Chemistry, College of Sciences, University of Kirkuk, Kirkuk, Iraq.
2 College of Dentistry, University of Kirkuk, Kirkuk, Iraq.
This study was involved synthesis of new bis oxazepinedione and bis
benzoxazepinedione compounds, derived from Schiff bases a(1-5). These Schiff
bases were prepared from hydrazine and diethyl succinate using ethanol as
solvent. The prepared Schiff bases have been undergone to reaction with maleic
anhydride and phthalic anhydride to form bis oxazepinedione b(1-5) and bis
benzoxazepinedione b(6-10) derivatives. The newly synthesized compounds
were characterized using spectroscopic techniques such as Carbon, Hydrogen
and Nitrogen (CHN) Elemental Analysis, Fourier transform infrared (FT-IR)
spectroscopy and proton nuclear magnetic resonance (
1H-NMR). The molecular
orbital package (MOPAC) method has been used to calculate heat of formation
(HF) and steric Energy (SE) for all of the synthesized chemicals. The (SE)
calculations were performed using the molecular modelling (MM2) method. The
MOPAC and MM2 methods are available in CS- Chemoffice-version 6.0
contains. The results indicated that compounds (a3, a4, b5 and b9) were shown
high stability and less steric effect. This may relate to the presence of donating
groups in the structure [OCH3 and N(CH3)2 ].